Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257281 | 0.80 | BCAT2 (0.49) | SMN1; SMN2LMNAMAPTPOLBRAB9A | |
| SCHEMBL8083083 | 0.78 | MAOB (0.47) | POLBRAB9A | |
| SCHEMBL9362874 | 0.76 | CYP2D6 (0.56) | LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL7763138 | 0.74 | KMT2A (0.50) | SMN1; SMN2LMNAMAPK1KMT2AMAPT | |
| SCHEMBL5682138 | 0.73 | ALDH1A1 (0.47) | SMN1; SMN2RAB9AALDH1A1NPC1HPGD | |
| SCHEMBL8938148 | 0.73 | BCAT2 (0.39) | POLBKIF11 | |
| SCHEMBL5509050 | 0.73 | MAPT (0.44) | SMN1; SMN2MAPK1KMT2AMAPTALDH1A1 | |
| SCHEMBL27339130 | 0.72 | KMT2A (0.41) | SMN1; SMN2PPIDLMNAMAPK1KMT2A | |
| SCHEMBL9262043 | 0.72 | PNMT (0.48) | SMN1; SMN2KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL2850028 | 0.72 | RIPK1 (0.49) | SMN1; SMN2LMNAKMT2AMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502078-A | Chemical compounds | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |