Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 7/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 2/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079904 | 0.88 | SRD5A2 (1.00) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8070861 | 0.83 | SRD5A2 (0.74) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8084624 | 0.81 | SRD5A2 (0.75) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8079953 | 0.81 | SRD5A2 (0.74) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8078572 | 0.78 | SRD5A2 (0.77) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8080226 | 0.75 | SRD5A2 (0.74) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8084620 | 0.71 | SRD5A2 (1.00) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8435551 | 0.71 | SRD5A2 (0.70) | SRD5A2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8070858 | 0.70 | SRD5A2 (1.00) | SRD5A2MEN1KMT2APKMNPC1 | |
| SCHEMBL8078523 | 0.69 | SRD5A2 (1.00) | SRD5A2MEN1KMT2APKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757982-B1 | Biphenylic compounds, process for their preparations and intermediates for this process, their use as 5-alpha-reductase inhibitors and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 2000-09-20 | — | — | EP | claimed |