Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 7/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079949 | 0.85 | SRD5A2 (1.00) | SRD5A2MEN1KMT2ATSHRBCHE | |
| SCHEMBL8070861 | 0.83 | SRD5A2 (0.74) | SRD5A2MEN1KMT2ATSHRPKM | |
| SCHEMBL8083145 | 0.81 | SRD5A2 (0.79) | SRD5A2MEN1KMT2ATSHRPKM | |
| SCHEMBL8080226 | 0.77 | SRD5A2 (0.74) | SRD5A2MEN1KMT2ATSHRPKM | |
| SCHEMBL8084624 | 0.71 | SRD5A2 (0.75) | SRD5A2MEN1KMT2ATSHRPKM | |
| SCHEMBL8070858 | 0.70 | SRD5A2 (1.00) | SRD5A2MEN1KMT2APKMNPC1 | |
| SCHEMBL8079934 | 0.70 | SRD5A2 (0.78) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL29843967 | 0.69 | SRD5A2 (0.54) | SRD5A2MEN1KMT2AESR1ALDH1A1 | |
| SCHEMBL8079904 | 0.69 | SRD5A2 (1.00) | SRD5A2MEN1KMT2APKMNPC1 | |
| SCHEMBL8078572 | 0.69 | SRD5A2 (0.77) | SRD5A2MEN1KMT2APKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757982-B1 | Biphenylic compounds, process for their preparations and intermediates for this process, their use as 5-alpha-reductase inhibitors and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 2000-09-20 | — | — | EP | claimed |