Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.52 |
| ▸ | MTOR | P42345 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1102393 | 0.75 | MEN1 (0.53) | HIF1AMEN1CYP1A2KMT2ACYP2D6 | |
| Pronetalol SCHEMBL31108442 | 0.73 | TSHR (1.00) | TSHRHIF1AMEN1CYP1A2KMT2A | |
| SCHEMBL12386886 | 0.73 | SMN1; SMN2 (0.47) | MEN1CYP1A2KMT2ACYP2D6MAPT | |
| Pronetalol SCHEMBL78996 | 0.73 | TSHR (1.00) | TSHRHIF1AMEN1CYP1A2KMT2A | |
| Pronetalol SCHEMBL9666931 | 0.73 | TSHR (1.00) | TSHRHIF1AMEN1CYP1A2KMT2A | |
| SCHEMBL30765633 | 0.72 | MAPT (0.55) | MEN1CYP1A2KMT2ACYP2D6MAPT | |
| SCHEMBL22787856 | 0.72 | MAPT (0.50) | MEN1CYP1A2KMT2ACYP2D6MAPT | |
| SCHEMBL30765515 | 0.72 | MAPT (0.55) | MEN1CYP1A2KMT2ACYP2D6MAPT | |
| SCHEMBL30765533 | 0.72 | MAPT (0.55) | MEN1CYP1A2KMT2ACYP2D6MAPT | |
| SCHEMBL3147148 | 0.72 | LMNA (0.50) | MEN1KMT2ACYP2D6MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063810-A | ENANTIOMORPHS | SYNTHELABO (FR) | 2000-05-16 | — | — | US | claimed |
| US-6063810-A | ENANTIOMORPHS | SYNTHELABO (FR) | 2000-05-16 | — | — | US | disclosed |