Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795559 | 0.67 | GRM5 (0.47) | GRM5NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL25177259 | 0.64 | GRM5 (0.57) | GRM5NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL808315 | 0.62 | SMN1; SMN2 (0.39) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL27775431 | 0.61 | GRIK1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL29901533 | 0.57 | CCR1 (0.52) | GRM5NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL28115227 | 0.57 | CCR1 (0.52) | GRM5NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL4188067 | 0.57 | GRM5 (0.72) | GRM5NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL4194624 | 0.57 | GRM5 (0.72) | GRM5NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL1424895 | 0.57 | TP53 (0.77) | GRM5NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL30821175 | 0.56 | GRM5 (1.00) | GRM5NPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |