Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807781 | 0.87 | ALDH1A1 (0.40) | SMN1; SMN2POLBTSHRCYP1A2CYP2C9 | |
| SCHEMBL807944 | 0.86 | MEN1 (0.38) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL808319 | 0.86 | NPC1 (0.43) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL10287136 | 0.78 | ALDH1A1 (0.41) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL10287533 | 0.68 | ADRA2A (0.33) | — | |
| SCHEMBL10287195 | 0.65 | MTOR (0.42) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL29959444 | 0.64 | TP53 (0.54) | RAB9ANPC1 | |
| SCHEMBL167713 | 0.63 | MEN1 (0.67) | TAAR1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL807993 | 0.62 | GRM5 (0.39) | SMN1; SMN2RAB9ANPC1SIGMAR1 | |
| SCHEMBL13906101 | 0.60 | MEN1 (0.62) | TAAR1KMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |