Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 12/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 4/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13002410 | 0.92 | CACNA1B (0.53) | CACNA1BNR1I2 | |
| SCHEMBL3485872 | 0.84 | CACNA1B (0.47) | CACNA1BGAAHPGDUBE2MDCUN1D1 | |
| SCHEMBL3485983 | 0.82 | UBE2M (0.48) | CACNA1BGAAHPGDUBE2MDCUN1D1 | |
| SCHEMBL3765384 | 0.80 | HPGD (0.48) | CACNA1BGAAHPGDUBE2MDCUN1D1 | |
| SCHEMBL3764979 | 0.78 | CACNA1B (0.47) | CACNA1BGAAHPGDUBE2MDCUN1D1 | |
| SCHEMBL3485722 | 0.78 | CACNA1B (0.50) | CACNA1BGAAHPGDLMNASMN1; SMN2 | |
| SCHEMBL13002406 | 0.77 | CACNA1B (0.51) | CACNA1BGAAHPGDUBE2MDCUN1D1 | |
| SCHEMBL13291497 | 0.77 | CACNA1B (0.49) | CACNA1BGAAHPGDLMNASMN1; SMN2 | |
| SCHEMBL3485159 | 0.76 | CACNA1B (0.50) | CACNA1BGAAHPGDNR1I2CACNA1C | |
| SCHEMBL8236293 | 0.76 | CACNA1B (0.51) | CACNA1BGAAHPGDNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009040659-A2 | BENZENESULFONAMIDE COMPOUNDS AND THE USE THEREOF | PURDUE PHARMA L.P. (DE) | 2009-04-02 | — | — | WO | disclosed |