SCHEMBL808334

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL795451	0.93	NAMPT (0.39)	MAP4K4MAPK1GSK3BNPC1RAB9A
	SCHEMBL796061	0.91	GRM5 (0.43)	SMN1; SMN2MEN1KMT2ANPC1RAB9A
	SCHEMBL796014	0.91	NPC1 (0.44)	SMN1; SMN2MEN1KMT2ANPC1RAB9A
	SCHEMBL808335	0.89	TP53 (0.39)	MAPK1POLBMAPTGSK3AGSK3B
	SCHEMBL793556	0.83	CDK2 (0.43)	MAPK1POLBMAPTGSK3AGSK3B
	SCHEMBL795741	0.82	SMN1; SMN2 (0.43)	MAPK1POLBMAPTGSK3AGSK3B
	SCHEMBL10286909	0.80	MAPK1 (0.34)	MAPK1POLBMAPTGSK3AGSK3B
	SCHEMBL15477324	0.80	MAPK1 (0.49)	MAPK1POLBMAPTSMN1; SMN2TP53
	SCHEMBL795967	0.79	NTRK1 (0.43)	MAPK1POLBMAPTSMN1; SMN2MEN1
	SCHEMBL795502	0.79	CYP2D6 (0.45)	MAPTGSK3AGSK3BSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.