Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.33 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708527 | 0.81 | NOTUM (0.36) | GRIN2BSLC1A5NOTUMGRIA1CACNG8 | |
| SCHEMBL23925112 | 0.81 | PTGER4 (0.35) | SLC1A5PDE2A | |
| SCHEMBL28056275 | 0.81 | GRIN2B (0.36) | GRIN2BSLC1A5NOTUMKMOPDE2A | |
| SCHEMBL30064335 | 0.81 | PTGER4 (0.35) | SLC1A5PDE2A | |
| SCHEMBL10934709 | 0.76 | NOTUM (0.42) | GRIN2BSLC1A5NOTUMGRIA1CACNG8 | |
| SCHEMBL21603543 | 0.76 | GRIA1 (0.42) | GRIN2BGRIA1CACNG8P2RX7 | |
| SCHEMBL29778856 | 0.76 | GRIA1 (0.42) | GRIN2BGRIA1CACNG8P2RX7 | |
| SCHEMBL29721858 | 0.75 | AKR1C2 (0.40) | KMOL3MBTL1EPHX2SCN9A | |
| SCHEMBL29006785 | 0.75 | AKR1C2 (0.40) | KMOL3MBTL1EPHX2SCN9A | |
| SCHEMBL29917977 | 0.75 | KMO (0.42) | KMOEPHX2SCN9AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820981-B1 | Process for the preparation of 2-trifluoromethoxy-aniline | BAYER AG (DE) | 2000-10-18 | — | — | EP | claimed |
| US-5840983-A | Process for preparing 2-trifluoromethoxy-aniline | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | claimed |
| EP-0820981-A1 | Process for the preparation of 2-trifluoromethoxy-aniline | BAYER AG (DE) | 1998-01-28 | — | — | EP | claimed |
| EP-0820981-B1 | Process for the preparation of 2-trifluoromethoxy-aniline | BAYER AG (DE) | 2000-10-18 | — | — | EP | disclosed |
| US-5840983-A | Process for preparing 2-trifluoromethoxy-aniline | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |
| EP-0820981-A1 | Process for the preparation of 2-trifluoromethoxy-aniline | BAYER AG (DE) | 1998-01-28 | — | — | EP | disclosed |
| EP-0820981-A1 | Process for the preparation of 2-trifluoromethoxy-aniline | BAYER AG (DE) | 1998-01-28 | — | — | EP | disclosed |