Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 9/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL8409534 | 1.00 | FDPS (0.39) | FDPSGGPS1LMNAALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL28020345 | 0.96 | FDPS (0.42) | FDPSGGPS1SMPD1 | |
| SCHEMBL16105662 | 0.94 | FDPS (0.43) | FDPSGGPS1TSHRSMPD1 | |
| SCHEMBL19709060 | 0.91 | FDPS (0.41) | FDPSGGPS1SMPD1 | |
| SCHEMBL16105722 | 0.84 | — | — | |
| Alcohol SCHEMBL10567295 | 0.75 | FDPS (0.46) | FDPSGGPS1LMNAALDH1A1HSD17B10 | |
| SCHEMBL5669042 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL11125691 | 0.74 | EPHX1 (0.37) | — | |
| SCHEMBL27892828 | 0.74 | FDPS (0.42) | FDPSGGPS1SMPD1 | |
| Heptane SCHEMBL1588905 | 0.74 | LMNA (0.56) | FDPSGGPS1LMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0615857-B1 | Recording sheets containing monoammonium compounds | XEROX CORP (US) | 1998-11-11 | — | — | EP | claimed |