SCHEMBL8083522

SCHEMBL8083522

Cc1ccc(C)c2c1C=C1CCC3=Cc4c(C)ccc(C)c4C3c3cc(C(F)(F)F)ccc3O[Zr]Oc3ccc(C(F)(F)F)cc3C12

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TERT O14746 1/20 0.33
PNMT P11086 1/20 0.32
HTR2A P28223 3/20 0.32
HTR2C P28335 3/20 0.32
HTR2B P41595 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5608741 0.76 CYP1A2 (0.34) PNMTHTR2AHTR2CHTR2B
SCHEMBL6684067 0.75 KMT2A (0.35) PNMTHTR2AHTR2CHTR2B
SCHEMBL8075360 0.74 PNMT (0.32) PNMT
SCHEMBL8083664 0.70 CYP1A2 (0.38) TERTPNMTHTR2AHTR2CHTR2B
SCHEMBL8086807 0.66 CYP1A2 (0.36) PNMT
SCHEMBL8082812 0.65 CYP1A2 (0.35)
SCHEMBL7891166 0.61
SCHEMBL25026228 0.60 CHRNB2 (0.47) PNMTHTR2AHTR2CHTR2B
SCHEMBL9270605 0.57 PNMT (0.39) TERTPNMT
SCHEMBL9270612 0.57 PNMT (0.39) TERTPNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1041084-A1 SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME MARUZEN PETROCHEMICAL CO., LTD. (JP) 2000-10-04 EP disclosed