Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331542 | 0.78 | LTA4H (0.45) | LTA4HTSHRSCN4ADPP4F2 | |
| SCHEMBL31590711 | 0.78 | LTA4H (0.45) | LTA4HTSHRSCN4ADPP4F2 | |
| SCHEMBL8145320 | 0.78 | LTA4H (0.45) | LTA4HTSHRCA4MAOACHRNB4 | |
| SCHEMBL6049880 | 0.78 | LTA4H (0.45) | LTA4HTSHRCA4MAOACHRNB4 | |
| SCHEMBL29270324 | 0.78 | LTA4H (0.45) | LTA4HTSHRSCN4ADPP4F2 | |
| SCHEMBL9819194 | 0.75 | KDM4E (0.41) | CA4MAOACHRNB4CHRNA3TAAR1 | |
| SCHEMBL24309913 | 0.74 | CA4 (0.43) | LTA4HTSHRSCN4ACA4MAOA | |
| SCHEMBL11072413 | 0.74 | TSHR (0.41) | LTA4HTSHRSCN4ADPP4F2 | |
| SCHEMBL16671569 | 0.74 | LMNA (0.41) | LTA4HTSHRCA4KCNA3KDM4E | |
| SCHEMBL10758577 | 0.74 | TSHR (0.41) | LTA4HTSHRCA4MAOAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846679-B1 | Process for preparing 1,3-disubstituted urea | SUMIKA FINE CHEMICALS CO LTD (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5902899-A | Process for preparing 1, 3-disubstituted urea | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0846679-A2 | Process for preparing 1,3-disubstituted urea | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1998-06-10 | — | — | EP | disclosed |