Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.56 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30039436 | 0.80 | GPR3 (0.58) | GPR3ALKBH5FTOMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL27415278 | 0.79 | ALDH1A1 (0.43) | GPR3MAPTNPC1SMN1; SMN2RECQL | |
| SCHEMBL483003 | 0.77 | GPR3 (0.61) | GPR3ALKBH5FTOMAPTALDH1A1 | |
| SCHEMBL31132408 | 0.77 | GPR3 (0.61) | GPR3ALKBH5FTOMAPTALDH1A1 | |
| SCHEMBL27947450 | 0.77 | GPR3 (0.54) | GPR3MAPTNPC1SMN1; SMN2RECQL | |
| SCHEMBL8083525 | 0.77 | GPR3 (0.54) | GPR3ALKBH5FTOMAPTNPC1 | |
| SCHEMBL28973482 | 0.76 | ALDH1A1 (0.55) | GPR3MAPTNPC1SMN1; SMN2ALDH1A1 | |
| Bromide SCHEMBL15569971 | 0.76 | GPR3 (0.58) | GPR3ALKBH5FTOMAPTALDH1A1 | |
| Iodide SCHEMBL344509 | 0.76 | GPR3 (0.58) | GPR3ALKBH5FTOMAPTALDH1A1 | |
| Bromide SCHEMBL15569972 | 0.76 | GPR3 (0.58) | GPR3ALKBH5FTOMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555537-B1 | Endothelin antagonists | BANYU PHARMA CO LTD (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |