Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 2/20 | 0.30 |
| ▸ | FPGS | Q05932 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091492 | 0.97 | CTSB (0.38) | CTSBHPGDS | |
| SCHEMBL8083599 | 0.93 | CTSB (0.34) | CTSBHPGDSDHFRFPGS | |
| SCHEMBL8083495 | 0.90 | CTSB (0.35) | CTSBHPGDS | |
| SCHEMBL8090117 | 0.89 | — | — | |
| SCHEMBL8097864 | 0.88 | CTSB (0.35) | CTSBHPGDS | |
| SCHEMBL8091555 | 0.87 | CTSB (0.33) | CTSBHPGDS | |
| SCHEMBL8090208 | 0.87 | CTSB (0.33) | CTSBHPGDS | |
| SCHEMBL8091545 | 0.86 | ITGB3 (0.31) | — | |
| SCHEMBL8098189 | 0.85 | CTSB (0.32) | CTSBHPGDS | |
| SCHEMBL8091403 | 0.85 | ITGB3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |