SCHEMBL8083606

SCHEMBL8083606

O=Cc1c(O)nc2ccccc2c1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 5/20 0.60
PADI4 Q9UM07 1/20 0.55
DHODH Q02127 3/20 0.40
PDE10A Q9Y233 1/20 0.40
ALDH1A1 P00352 4/20 0.37
LMNA P02545 1/20 0.37
MAOA P21397 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GLA P06280 1/20 0.36
CHRM2 P08172 1/20 0.36
ADRA2A P08913 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CHRM1 P11229 1/20 0.36
HPGD P15428 1/20 0.36
NQO2 P16083 1/20 0.36
DRD1 P21728 1/20 0.36
ACHE P22303 1/20 0.36
SLC6A2 P23975 1/20 0.36
CASP1 P29466 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11416237 0.82 ERN1 (0.76) ERN1PADI4PDE10AALDH1A1LMNA
SCHEMBL11435110 0.79 ERN1 (0.41) ERN1PADI4DHODHPDE10AALDH1A1
SCHEMBL8878762 0.78 ERN1 (0.53) ERN1PADI4DHODHPDE10AALDH1A1
SCHEMBL12693813 0.78 ERN1 (0.53) ERN1PADI4ALDH1A1LMNAKDM4E
SCHEMBL11974118 0.76 KMT2A (0.54) ALDH1A1LMNASMN1; SMN2KDM4ETDP1
SCHEMBL11907327 0.76 KMT2A (0.54) ALDH1A1LMNASMN1; SMN2KDM4ETDP1
SCHEMBL30196788 0.76 KMT2A (0.54) ALDH1A1LMNASMN1; SMN2KDM4ETDP1
SCHEMBL10536051 0.76 KMT2A (0.54) ALDH1A1LMNASMN1; SMN2KDM4ETDP1
SCHEMBL10436994 0.76 ALB (0.47) ERN1DHODHALDH1A1LMNASMN1; SMN2
SCHEMBL11423296 0.76 ALB (0.47) ERN1PADI4DHODHALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640591-B1 Azomethine derivatives as UV light absorbers ORIENT CHEMICAL IND (JP) 2000-11-02 EP disclosed
US-5523027-A AZOMETHINE COMPOUNDS; LIGHT RESISTANCE ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1996-06-04 US disclosed
EP-0640591-A1 Azomethine derivatives as UV light absorbers ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1995-03-01 EP disclosed
EP-0354178-A1 Thermoplastics containing a metal complex pigment CIBA-GEIGY AG (CH) 1990-02-07 EP disclosed
US-4866112-A BISAZOLMETHINE WITH DIOXYQUINOLINYL RADICALS AS LIGAND CIBA-GEIGY CORPORATION (US) 1989-09-12 US disclosed
EP-0159962-B1 FIBRE-REACTIVE CHROMIUM OR COBALT COMPLEXES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1989-02-08 EP disclosed
US-4680385-A Metal dye complexes containing an azo or azomethine dye and a colorless ligand with the C═N--N═C group CIBA-GEIGY CORPORATION (US) 1987-07-14 US disclosed
US-4678851-A FIBER-RACTIVE CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
EP-0159962-A2 Fibre-reactive chromium or cobalt complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-10-30 EP disclosed
US-4237286-A COLORING PLASTICS AND LACQUERS IN YELLOW TO RED SHADES CIBA-GEIGY CORPORATION (US) 1980-12-02 US disclosed
US-4144258-A ORGANIC PIGMENTS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1979-03-13 US disclosed
US-4132708-A Metal complexes of azomethines and process for their manufacture CIBA-GEIGY CORPORATION (US) 1979-01-02 US disclosed
US-4111947-A DYES, PLASTICS, LACQUERS CIBA-GEIGY CORPORATION (US) 1978-09-05 US disclosed
US-4065481-A 1:1-Azomethine-metal-complex dyestuffs CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4024132-A Azomethine pigments CIBA-GEIGY CORPORATION (US) 1977-05-17 US disclosed
US-4022770-A COLORING CIBA-GEIGY CORPORATION (US) 1977-05-10 US disclosed
US-4016157-A COLORING PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1977-04-05 US disclosed
US-3988323-A PIGMENTS CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed
US-3980640-A YELLOW PIGMENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-09-14 US disclosed
US-3974149-A TONERS CIBA-GEIGY CORPORATION (US) 1976-08-10 US disclosed