SCHEMBL11435110

SCHEMBL11435110

NN=Cc1c(O)nc2ccccc2c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.41
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 4/20 0.38
GLA P06280 3/20 0.38
HPGD P15428 2/20 0.38
CASP1 P29466 2/20 0.38
CASP7 P55210 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MAOA P21397 2/20 0.38
CHRM2 P08172 1/20 0.38
ADRA2A P08913 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
CHRM1 P11229 1/20 0.38
NQO2 P16083 1/20 0.38
DRD1 P21728 1/20 0.38
ACHE P22303 1/20 0.38
SLC6A2 P23975 1/20 0.38
ADRA1A P35348 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30196788 0.83 KMT2A (0.54) KDM4EALDH1A1SMN1; SMN2TDP1RAB9A
SCHEMBL11974118 0.83 KMT2A (0.54) KDM4EALDH1A1SMN1; SMN2TDP1RAB9A
SCHEMBL11907327 0.83 KMT2A (0.54) KDM4EALDH1A1SMN1; SMN2TDP1RAB9A
SCHEMBL10536051 0.83 KMT2A (0.54) KDM4EALDH1A1SMN1; SMN2TDP1RAB9A
SCHEMBL8083606 0.79 ERN1 (0.60) ERN1KDM4EALDH1A1GLAHPGD
SCHEMBL24213316 0.75 MAPT (0.45) KDM4EALDH1A1TDP1RAB9AKMT2A
SCHEMBL30196628 0.75 MAPT (0.45) KDM4EALDH1A1TDP1RAB9AKMT2A
SCHEMBL23668744 0.75 MAPT (0.45) KDM4EALDH1A1TDP1RAB9AKMT2A
SCHEMBL17153341 0.74 ALDH1A1 (0.47) KDM4EALDH1A1HPGDKMT2AMAPT
SCHEMBL851828 0.73 KDM4E (0.44) ERN1KDM4EALDH1A1GLAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4237292-A SHADES OF YELLOW TO RED FOR PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1980-12-02 US disclosed
US-4237293-A COLORFAST SHADES OF YELLOW TO RED FOR PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1980-12-02 US disclosed
US-4237286-A COLORING PLASTICS AND LACQUERS IN YELLOW TO RED SHADES CIBA-GEIGY CORPORATION (US) 1980-12-02 US disclosed
US-4132708-A Metal complexes of azomethines and process for their manufacture CIBA-GEIGY CORPORATION (US) 1979-01-02 US disclosed
US-4111947-A DYES, PLASTICS, LACQUERS CIBA-GEIGY CORPORATION (US) 1978-09-05 US disclosed
US-4022770-A COLORING CIBA-GEIGY CORPORATION (US) 1977-05-10 US disclosed