SCHEMBL11907327

SCHEMBL11907327

Oc1nc2ccccc2c(O)c1/C=N/c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.54
MAPT P10636 8/20 0.54
MEN1 O00255 8/20 0.49
HKDC1 Q2TB90 1/20 0.49
RAB9A P51151 3/20 0.49
NPC1 O15118 2/20 0.49
KDM4E B2RXH2 5/20 0.48
GAA P10253 3/20 0.48
POLB P06746 2/20 0.48
THRB P10828 1/20 0.48
BLM P54132 1/20 0.48
CASP6 P55212 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ALDH1A1 P00352 7/20 0.45
USP2 O75604 1/20 0.44
ALOX12 P18054 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10536051 1.00 KMT2A (0.54) KMT2AMAPTMEN1HKDC1RAB9A
SCHEMBL11974118 1.00 KMT2A (0.54) KMT2AMAPTMEN1HKDC1RAB9A
SCHEMBL30196788 1.00 KMT2A (0.54) KMT2AMAPTMEN1HKDC1RAB9A
SCHEMBL24213316 0.87 MAPT (0.45) KMT2AMAPTMEN1HKDC1RAB9A
SCHEMBL30196628 0.87 MAPT (0.45) KMT2AMAPTMEN1HKDC1RAB9A
SCHEMBL23668744 0.87 MAPT (0.45) KMT2AMAPTMEN1HKDC1RAB9A
SCHEMBL17153341 0.86 ALDH1A1 (0.47) KMT2AMAPTMEN1HKDC1KDM4E
SCHEMBL11435110 0.83 ERN1 (0.41) KMT2AMAPTMEN1HKDC1RAB9A
SCHEMBL10536094 0.83 KMT2A (0.45) KMT2AMAPTMEN1HKDC1RAB9A
SCHEMBL10538034 0.83 KMT2A (0.43) KMT2AMAPTMEN1HKDC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230145740-A1 OPTICAL FILTER AGC Inc. (JP) 2023-05-11 US disclosed
US-20230145740-A1 OPTICAL FILTER AGC Inc. (JP) 2023-05-11 US disclosed
US-20220017474-A1 Novel Polycyclic Compound EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) 2022-01-20 US disclosed
EP-3896067-A1 NOVEL POLYCYCLIC COMPOUND Eutec New Materials Technology (Suzhou) Co., Ltd (CN) 2021-10-20 EP disclosed
US-20210230128-A1 ANTI-BLUE LIGHT COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) 2021-07-29 US disclosed
US-11029457-B2 Optical filter AGC Inc. (JP) 2021-06-08 US disclosed
WO-2020118933-A1 NOVEL POLYCYCLIC COMPOUND 优缔新材料科技(苏州)有限公司 2020-06-18 WO disclosed
US-20190227208-A1 OPTICAL FILTER AGC Inc. (JP) 2019-07-25 US disclosed
US-10324240-B2 Optical filter AGC Inc. (JP) 2019-06-18 US disclosed
US-20170184765-A1 OPTICAL FILTER ASAHI GLASS COMPANY, LIMITED (JP) 2017-06-29 US disclosed
US-20170184765-A1 OPTICAL FILTER ASAHI GLASS COMPANY, LIMITED (JP) 2017-06-29 US disclosed
US-20140212792-A1 HOLOGRAPHIC STORAGE MEDIUM AND METHOD OF MAKING HOLOGRAPHIC STORAGE MEDIUM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-07-31 US disclosed
US-8728685-B2 Method of making holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-05-20 US disclosed
EP-2676170-A1 HOLOGRAPHIC STORAGE MEDIUM AND METHOD OF MAKING HOLOGRAPHIC STORAGE MEDIUM SABIC Innovative Plastics IP B.V. (NL) 2013-12-25 EP disclosed
WO-2012138421-A1 HOLOGRAPHIC STORAGE MEDIUM AND METHOD OF MAKING HOLOGRAPHIC STORAGE MEDIUM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-10-11 WO disclosed
US-20120208110-A1 HOLOGRAPHIC STORAGE MEDIUM AND METHOD OF MAKING HOLOGRAPHIC STORAGE MEDIUM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210230128-A1 ANTI-BLUE LIGHT COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF UACA, CRY2, SUN2 KMT2A 3785/4885MAPT 52/4885MEN1 1688/4885
US-20220017474-A1 Novel Polycyclic Compound CUTA, DSG1, UACA KMT2A 2775/4885MAPT 295/4885MEN1 639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.