Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083582 | 0.87 | SPHK1 (0.39) | KDM1AHTTSMN1; SMN2SPHK1MAOB | |
| SCHEMBL8098206 | 0.84 | C3AR1 (0.35) | KDM1AHTTSMN1; SMN2MAOBCXCR3 | |
| SCHEMBL8098215 | 0.83 | C3AR1 (0.37) | KDM1AHTTSMN1; SMN2CXCR3TPSAB1 | |
| SCHEMBL8083456 | 0.83 | MMP8 (0.46) | SPHK1TPSAB1MMP8 | |
| SCHEMBL8083610 | 0.83 | MMP8 (0.54) | SPHK1MMP8 | |
| SCHEMBL8089921 | 0.83 | MMP8 (0.48) | SPHK1MMP8 | |
| SCHEMBL8083488 | 0.82 | MMP8 (0.45) | SPHK1MMP8 | |
| SCHEMBL7445671 | 0.82 | F2 (0.34) | KDM1ACXCR3TPSAB1 | |
| SCHEMBL8083554 | 0.81 | MMP8 (0.46) | SMN1; SMN2SPHK1TPSAB1MMP8 | |
| SCHEMBL7443581 | 0.79 | SMN1; SMN2 (0.43) | HTTSMN1; SMN2BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |