Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | RBBP5 | Q15291 | 1/20 | 0.35 |
| ▸ | DPY30 | Q9C005 | 1/20 | 0.35 |
| ▸ | ASH2L | Q9UBL3 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083629 | 0.87 | KDM1A (0.40) | SPHK1KDM1AMAOBHTTSMN1; SMN2 | |
| SCHEMBL8095479 | 0.86 | F2 (0.37) | KDM1AMAOBF7PTBP1KMT2A | |
| SCHEMBL8083610 | 0.82 | MMP8 (0.54) | SPHK1KMT2AL3MBTL1MMP8HPGD | |
| SCHEMBL8083456 | 0.82 | MMP8 (0.46) | SPHK1MMP8HPGD | |
| SCHEMBL8089921 | 0.82 | MMP8 (0.48) | SPHK1KMT2AMMP8 | |
| SCHEMBL8083488 | 0.81 | MMP8 (0.45) | SPHK1MMP8HPGD | |
| SCHEMBL8083554 | 0.80 | MMP8 (0.46) | SPHK1SMN1; SMN2MMP8HPGD | |
| SCHEMBL8098206 | 0.77 | C3AR1 (0.35) | KDM1AMAOBHTTSMN1; SMN2 | |
| SCHEMBL8095062 | 0.77 | MMP8 (0.48) | SPHK1SMN1; SMN2MMP8HPGD | |
| SCHEMBL7433719 | 0.76 | F2 (0.43) | SPHK1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | claimed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | claimed |