Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | RECQL | P46063 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25288808 | 0.88 | RAB9A (0.73) | MAPTRECQLGAAGFERALDH1A1 | |
| SCHEMBL31084666 | 0.88 | RAB9A (0.73) | MAPTRECQLGAAGFERALDH1A1 | |
| SCHEMBL6040790 | 0.86 | MAPT (0.75) | MAPTRECQLGAAGFERALDH1A1 | |
| SCHEMBL19626555 | 0.82 | MAPT (0.69) | MAPTRECQLGAAGFERALDH1A1 | |
| SCHEMBL13367649 | 0.82 | ALDH1A1 (0.74) | MAPTRECQLGAAGFERALDH1A1 | |
| SCHEMBL8081684 | 0.81 | MAPT (0.64) | MAPTRECQLGAAGFERALDH1A1 | |
| SCHEMBL3346281 | 0.81 | RECQL (0.61) | MAPTRECQLGAAGFERALDH1A1 | |
| SCHEMBL7811998 | 0.78 | MAPT (0.64) | MAPTRECQLGAAGFERALDH1A1 | |
| SCHEMBL12021849 | 0.78 | RECQL (0.58) | MAPTRECQLGAAGFERALDH1A1 | |
| SCHEMBL4094288 | 0.78 | RECQL (0.58) | MAPTRECQLGAAGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836596-B1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEM CO INC (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0836596-A1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002257-A1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-01-23 | — | — | WO | disclosed |