Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408608 | 0.76 | — | — | |
| SCHEMBL8083739 | 0.71 | — | — | |
| SCHEMBL10877482 | 0.71 | — | — | |
| SCHEMBL3482047 | 0.69 | ALDH1A1 (0.37) | TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL6814446 | 0.67 | TSHR (0.48) | TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL4685011 | 0.67 | — | — | |
| SCHEMBL30395263 | 0.67 | TSHR (0.48) | TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL26316534 | 0.65 | — | — | |
| SCHEMBL1342478 | 0.65 | — | — | |
| SCHEMBL301344 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633265-B1 | Process for preparation of beta-cyanoalkylsilanes | DOW CORNING (US) | 2000-10-25 | — | — | EP | disclosed |
| EP-0525997-B1 | Catalysts for addition of silicon hydrides to alpha, beta-unsaturated olefinic nitriles | DOW CORNING (US) | 1996-08-21 | — | — | EP | disclosed |
| EP-0633265-A1 | Process for preparation of beta-cyanoalkylsilanes | DOW CORNING CORPORATION (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5283348-A | Process for preparation of β-cyanoalkylsilanes | DOW CORNING CORPORATION (US) | 1994-02-01 | — | — | US | disclosed |
| EP-0525997-A1 | Catalysts for addition of silicon hydrides to alpha, beta-unsaturated olefinic nitriles | DOW CORNING CORPORATION (US) | 1993-02-03 | — | — | EP | disclosed |
| EP-0520645-A1 | Process for preparation of beta-cyanoalkylsilanes | DOW CORNING CORPORATION (US) | 1992-12-30 | — | — | EP | disclosed |
| US-5126469-A | Supported catalysts for addition of silicon hydrides to α,β-unsaturated olefinic nitriles | DOW CORNING CORPORATION (US) | 1992-06-30 | — | — | US | disclosed |
| US-5126468-A | Diamine and copper or copper compound | DOW CORNING CORPORATION (US) | 1992-06-30 | — | — | US | disclosed |
| US-5103033-A | Catalytic reaction of unsaturated nitriles and silicon hydride | DOW CORNING CORPORATION (US) | 1992-04-07 | — | — | US | disclosed |