SCHEMBL8083783

SCHEMBL8083783

CCC(Oc1ccc(C)cc1C(C)(C)CC)C(=O)Nc1cc(Cl)c(C)c(Cl)c1O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
POLB P06746 2/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
ALDH1A1 P00352 3/20 0.33
PKM P14618 1/20 0.33
MAPK14 Q16539 1/20 0.32
ACACB O00763 1/20 0.32
MAPT P10636 2/20 0.31
NPSR1 Q6W5P4 4/20 0.31
LMNA P02545 2/20 0.31
MCOLN3 Q8TDD5 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7704204 0.92 NPSR1 (0.40) TSHRPOLBGAAKMT2AMEN1
SCHEMBL8088633 0.91 TSHR (0.33) TSHRPOLBGAAKMT2AMEN1
SCHEMBL12774725 0.86 NPSR1 (0.38) TSHRPOLBGAAKMT2AMEN1
SCHEMBL11513749 0.86 ACACB (0.37) TSHRPOLBGAAKMT2AMEN1
SCHEMBL9153381 0.85 TSHR (0.37) TSHRPOLBGAAKMT2AMEN1
SCHEMBL11528814 0.85 NPSR1 (0.41) TSHRPOLBGAAKMT2AMEN1
SCHEMBL8075435 0.84 MAPK1 (0.39) KMT2AMEN1ALDH1A1MAPK14ACACB
SCHEMBL11754837 0.84 NPSR1 (0.40) TSHRPOLBGAAKMT2AMEN1
SCHEMBL11421800 0.83 MAPK1 (0.39) TSHRPOLBGAAKMT2AMEN1
SCHEMBL8083293 0.83 MAPK1 (0.38) KMT2AMEN1ALDH1A1MAPK14ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0608896-B2 Process for producing aromatic amide compounds useful as cyan coupler for color photographs SUMITOMO CHEMICAL CO (JP) 2000-11-02 EP disclosed
US-5442114-A Process for producing aromatic amide compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-08-15 US disclosed
EP-0608896-A1 Process for producing aromatic amide compounds useful as cyan coupler for color photographes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-08-03 EP disclosed