SCHEMBL8083792

SCHEMBL8083792

COC1=CC(=O)C(C(=O)O)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
CYP1A2 P05177 2/20 0.38
KDM1A O60341 1/20 0.38
MAOA P21397 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38
CYP3A4 P08684 2/20 0.36
CA1 P00915 1/20 0.34
CA9 Q16790 1/20 0.34
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
GAA P10253 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
TP53 P04637 1/20 0.30
THRB P10828 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7729951 0.83 ALDH1A1 (0.40) ALDH1A1MAPTKDM1AMAOASMN1; SMN2
SCHEMBL3841075 0.70 CA1 (0.36) CA1CA9L3MBTL1
SCHEMBL15905705 0.67 CYP3A4 (0.36) ALDH1A1MAPTCYP1A2KDM1AMAOA
SCHEMBL8578810 0.63 CA12 (0.35) ALDH1A1MAPTCYP1A2KDM1AMAOA
SCHEMBL8578815 0.63 CA12 (0.35) ALDH1A1MAPTCYP1A2KDM1AMAOA
SCHEMBL10862568 0.63 ALDH1A1 (0.34) ALDH1A1MAPT
SCHEMBL12902073 0.61 ALDH1A1 (0.41) ALDH1A1MAPTCYP1A2HIF1ACA1
SCHEMBL18272609 0.61 CA1 (0.30) CA1GAA
SCHEMBL4611943 0.61
SCHEMBL5521616 0.60 CYP1A2 (0.41) ALDH1A1CYP1A2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed