Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 5/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083851 | 1.00 | MAOB (0.38) | MAOBTSHRHSD17B10HRH3RARB | |
| SCHEMBL7771579 | 0.90 | MAOB (0.40) | MAOBTSHRHSD17B10HRH3RARB | |
| SCHEMBL7771574 | 0.90 | MAOB (0.40) | MAOBTSHRHSD17B10HRH3RARB | |
| SCHEMBL7762415 | 0.88 | ITGB3 (0.39) | HSD17B10 | |
| SCHEMBL7762419 | 0.88 | ITGB3 (0.39) | HSD17B10 | |
| SCHEMBL8092153 | 0.88 | MAOB (0.43) | MAOB | |
| SCHEMBL8092154 | 0.88 | MAOB (0.43) | MAOB | |
| SCHEMBL7762593 | 0.87 | ITGB3 (0.41) | HSD17B10 | |
| SCHEMBL7762600 | 0.87 | ITGB3 (0.41) | HSD17B10 | |
| SCHEMBL7755798 | 0.85 | MAOB (0.43) | MAOBPSMD14HSP90AA1MMP2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668286-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-12-20 | — | — | EP | disclosed |
| US-5523440-A | Silacyclohexane compound, a method of preparaing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0668286-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-08-23 | — | — | EP | disclosed |