Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651586 | 0.72 | HTR2A (0.40) | HTR6HTR2A | |
| SCHEMBL7029100 | 0.71 | TRPA1 (0.30) | — | |
| SCHEMBL8083898 | 0.71 | HTR2A (0.36) | HTR6HTR2A | |
| SCHEMBL9144861 | 0.70 | HTR2A (0.39) | HTR6HTR2A | |
| Lithium SCHEMBL9142074 | 0.70 | HTR2A (0.39) | HTR6HTR2A | |
| SCHEMBL8668908 | 0.70 | HTR2A (0.39) | HTR6HTR2A | |
| SCHEMBL9142060 | 0.70 | HTR2A (0.39) | HTR6HTR2A | |
| SCHEMBL9144853 | 0.70 | HTR2A (0.39) | HTR6HTR2A | |
| SCHEMBL7029138 | 0.69 | — | — | |
| SCHEMBL4652559 | 0.69 | HTR2A (0.38) | HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376154-B2 | Bisindenyl derivative and method for its preparation | TARGOR GMBH (DE) | 2000-09-27 | — | — | EP | disclosed |
| EP-0692486-A2 | Bisindenyl derivative and process for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |
| US-4985576-A | Bisindenyl derivative, and a process for the preparation thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0376154-A2 | Bisindenyl derivative and method for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-04 | — | — | EP | disclosed |