Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 15/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570373 | 0.85 | P2RX7 (0.72) | HSD17B10KMT2AP2RX7TSHRHTT | |
| SCHEMBL7517360 | 0.84 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL8080956 | 0.84 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL8080894 | 0.84 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL6497265 | 0.84 | P2RX7 (0.56) | HPGDP2RX7 | |
| SCHEMBL7690936 | 0.84 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL4095273 | 0.84 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL7077870 | 0.82 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL8071731 | 0.81 | P2RX7 (0.65) | P2RX7 | |
| SCHEMBL7556017 | 0.81 | P2RX7 (0.53) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036059-A1 | ADAMANTANE DERIVATIVES | AstraZeneca UK Limited (GB) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999029661-A1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LIMITED (GB) | 1999-06-17 | — | — | WO | disclosed |