Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 10/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085107 | 0.89 | ABCC9 (0.44) | ABCC9KMT2AMAPTGAAMEN1 | |
| SCHEMBL8085123 | 0.87 | ABCC9 (0.45) | ABCC9KMT2AMAPTGAAMEN1 | |
| SCHEMBL8085336 | 0.86 | ABCC9 (0.49) | ABCC9 | |
| SCHEMBL8090747 | 0.86 | ABCC9 (0.49) | ABCC9 | |
| SCHEMBL8084911 | 0.85 | ABCC9 (0.46) | ABCC9KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8088858 | 0.84 | ABCC9 (0.47) | ABCC9LMNA | |
| SCHEMBL8084366 | 0.84 | ABCC9 (0.54) | ABCC9LMNA | |
| SCHEMBL8077294 | 0.83 | KMT2A (0.41) | KMT2AMAPTGAAMEN1PKM | |
| SCHEMBL8085350 | 0.82 | ABCC9 (0.46) | ABCC9GAASMN1; SMN2LMNA | |
| SCHEMBL8088369 | 0.80 | ABCC9 (0.49) | ABCC9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5387587-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| EP-0273262-A2 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |