SCHEMBL8084262

SCHEMBL8084262

CC1Cc2ccc3ccccc3c2C1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.50
POLB P06746 1/20 0.44
HTR1A P08908 2/20 0.41
HTR7 P34969 2/20 0.41
ALDH1A1 P00352 5/20 0.41
HSD17B10 Q99714 3/20 0.41
CYP2A6 P11509 2/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HIF1A Q16665 1/20 0.40
CYP1B1 Q16678 1/20 0.40
ACHE P22303 1/20 0.39
CYP1A2 P05177 1/20 0.39
HPGD P15428 1/20 0.39
HPRT1 P00492 1/20 0.38
KDM4E B2RXH2 1/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
RCE1 Q9Y256 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29084579 0.84 HTR7 (0.48) ANPEPPOLBHTR1AHTR7ALDH1A1
SCHEMBL19116646 0.77 ANPEP (0.50) ANPEPHTR1AHTR7ALDH1A1HSD17B10
SCHEMBL21096083 0.74 KDM4E (0.41) ALDH1A1TSHRCYP1A2KDM4EGAA
SCHEMBL14198149 0.73 ANPEP (0.43) ANPEPHTR7ALDH1A1KDM4E
SCHEMBL6990855 0.72 KDM4E (0.57) ANPEPALDH1A1HIF1ACYP1A2KDM4E
SCHEMBL20912271 0.72 ALDH1A1 (0.40) ANPEPPOLBHTR1AHTR7ALDH1A1
SCHEMBL9515050 0.72 ANPEP (0.53) ANPEPALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL9515057 0.72 ANPEP (0.53) ANPEPALDH1A1HSD17B10CYP2A6TSHR
Hydrochloric Acid SCHEMBL9516290 0.70 ANPEP (0.51) ANPEPALDH1A1HSD17B10CYP2A6TSHR
Hydrochloric Acid SCHEMBL9516294 0.70 ANPEP (0.51) ANPEPALDH1A1HSD17B10CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0854876-A2 PRODUCTION OF BRIDGED METALLOCENE COMPLEXES AND INTERMEDIATES THEREFOR ALBEMARLE CORPORATION (US) 1998-07-29 EP claimed
WO-1997049712-A2 PRODUCTION OF BRIDGED METALLOCENE COMPLEXES AND INTERMEDIATES THEREFOR ALBEMARLE CORPORATION (US) 1997-12-31 WO claimed
US-6087536-A Preparation of indene derivatives BASF AKTIENGESELLSCHAFT (DE) 2000-07-11 US disclosed
EP-0826654-B1 Process for the preparation of derivatives of indene BASF AG (DE) 1999-01-13 EP disclosed
EP-0826654-A1 Process for the preparation of derivatives of indene BASF AKTIENGESELLSCHAFT (DE) 1998-03-04 EP disclosed
EP-0739346-A1 USE OF GEL-FREE ALUMOXANE SOLUTION EXXON CHEMICAL PATENTS INC. (US) 1996-10-30 EP disclosed
WO-1995018809-A1 USE OF GEL-FREE ALUMOXANE SOLUTION EXXON CHEMICAL PATENTS INC. (US) 1995-07-13 WO disclosed