Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084473 | 0.84 | SOS1 (0.53) | HTR1DHTR1BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL6983805 | 0.79 | CHRM1 (0.61) | CHRM1SLC6A2SLC6A4 | |
| SCHEMBL8400707 | 0.71 | ALDH1A1 (0.56) | — | |
| SCHEMBL18952149 | 0.71 | SLC6A4 (0.43) | CHRM1SLC6A2SLC6A4 | |
| SCHEMBL20144687 | 0.69 | GAA (0.56) | ADRB2 | |
| SCHEMBL8630688 | 0.69 | TACR1 (0.48) | — | |
| SCHEMBL8630684 | 0.69 | TACR1 (0.48) | — | |
| SCHEMBL20144711 | 0.68 | GAA (0.54) | ADRB2 | |
| SCHEMBL7891599 | 0.68 | ITGB3 (0.38) | — | |
| SCHEMBL28426623 | 0.68 | MEN1 (0.41) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998440-A | Azetidine, pyrrolidine and piperidine derivatives | MERCK SHARPE & DOHME LTD. (GB) | 1999-12-07 | — | — | US | disclosed |