Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277693 | 0.87 | MAPK1 (0.57) | KMT2AMAPK1LMNAL3MBTL1TSHR | |
| SCHEMBL7216584 | 0.82 | CA1 (0.48) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL6272279 | 0.82 | KDM4E (0.51) | KMT2AMAPK1LMNAKDM4E | |
| SCHEMBL237041 | 0.82 | KDM4E (0.51) | KMT2ALMNAL3MBTL1MAPTKDM4E | |
| 1,3-Dipropoxybenzene SCHEMBL73716 | 0.82 | KMT2A (0.63) | KMT2AGPBAR1CYSLTR1MAPK1LMNA | |
| SCHEMBL7010041 | 0.81 | CHRM5 (0.45) | L3MBTL1 | |
| SCHEMBL7976554 | 0.80 | KCNA3 (0.52) | KMT2AL3MBTL1MAPT | |
| SCHEMBL6277285 | 0.80 | KDM4E (0.55) | KMT2ALMNATSHRKDM4E | |
| SCHEMBL2139475 | 0.80 | MAOA (0.51) | KMT2AL3MBTL1 | |
| SCHEMBL10796629 | 0.78 | KMT2A (0.61) | KMT2AKAT6AGPBAR1CYSLTR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045826-A1 | PROCESS FOR THE PREPARATION OF ISOPROPYL-METHYL- 2-(3-N-PROPOXYPHENOXY)ETHYL]AMINE | AstraZeneca AB (SE) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999032430-A1 | PROCESS FOR THE PREPARATION OF ISOPROPYL-METHYL-[2-(3-N-PROPOXYPHENOXY)ETHYL]AMINE | ASTRAZENECA AB (SE) | 1999-07-01 | — | — | WO | disclosed |