SCHEMBL7976554

SCHEMBL7976554

CS(=O)(=O)OCCOc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.52
PKM P14618 2/20 0.52
MEN1 O00255 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
MAPT P10636 1/20 0.47
RAB9A P51151 1/20 0.47
HTR1B P28222 2/20 0.47
HTR1D P28221 1/20 0.47
ALDH1A1 P00352 2/20 0.47
TAAR1 Q96RJ0 1/20 0.47
RECQL P46063 1/20 0.47
PARP10 Q53GL7 1/20 0.46
LTA4H P09960 1/20 0.46
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
CHRNB2 P17787 1/20 0.44
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
CHRNA7 P36544 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3939161 0.94 PKM (0.47) KCNA3PKMMEN1HTTKMT2A
SCHEMBL9714281 0.93 LTA4H (0.58) KCNA3PKMMEN1HTTKMT2A
SCHEMBL4741970 0.90 KCNA3 (0.56) KCNA3PKMMEN1HTTKMT2A
SCHEMBL6230016 0.89 KCNA3 (0.59) KCNA3MEN1HTTKMT2AHTR1B
SCHEMBL10391332 0.88 KCNA3 (0.48) KCNA3PKMMEN1HTTKMT2A
SCHEMBL24041771 0.86 CA1 (0.53) PKMMEN1HTTKMT2ARAB9A
SCHEMBL8633888 0.84 SMN1; SMN2 (0.48) MEN1KMT2ARAB9AALDH1A1MTNR1A
SCHEMBL13530003 0.84 GAA (0.62) PKMHTTMAPTRAB9AALDH1A1
SCHEMBL1607270 0.83 KCNA3 (0.56) KCNA3PKMMAPTRAB9AHTR1B
SCHEMBL6277239 0.82 L3MBTL1 (0.49) PKMMEN1HTTKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250026779-A1 ETHYL MODIFIED RNA CAPS AND METHODS OF USE MEDICI THERAPEUTICS, INC. 2025-01-23 US disclosed
CN-106432098-B Carbamate compound and its preparation method and application 华中师范大学 2018-09-18 CN disclosed
US-20170349621-A1 TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME BioVersys AG (CH) 2017-12-07 US disclosed
US-9585891-B2 Alpha hydroxy amides MERCK PATENT GMBH (DE) 2017-03-07 US disclosed
CN-106432098-A Carbamate compound and preparation method and application thereof 华中师范大学 2017-02-22 CN disclosed
US-20150250792-A1 ALPHA HYDROXY AMIDES MERCK PATENT GMBH (DE) 2015-09-10 US disclosed
EP-2900633-A1 ALPHA HYDROXY AMIDES Merck Patent GmbH (DE) 2015-08-05 EP disclosed
US-9085600-B2 Triazole compounds and methods of making and using the same MELINTA THERAPEUTICS, INC. (US) 2015-07-21 US disclosed
US-20150158901-A1 MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME BioVersys AG (CH) 2015-06-11 US disclosed
US-9000043-B2 Phenoxyethoxy compounds ELI LILLY AND COMPANY (US) 2015-04-07 US disclosed
US-6235731-B1 REDUCING BLOOD LIPIDS, SUGARS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-05-22 US disclosed
US-5962743-A Process for preparing acylaromatic compounds CATALYTICA PHARMACEUTICALS, INC. (US) 1999-10-05 US disclosed
EP-0915888-A1 FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS Takeda Chemical Industries, Ltd. (JP) 1999-05-19 EP disclosed
WO-1997040051-A1 FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-10-30 WO disclosed
US-5587383-A CALMODULIN INHIBITORS; ANTIISCHEMIC AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-12-24 US disclosed
EP-0471236-B1 Imidazopyridine derivatives and their use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-03-15 EP disclosed
US-5395839-A Calmodulin and angiogenesis inhibitors TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-03-07 US disclosed
US-5244908-A Calmodulin inhibitors TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-09-14 US disclosed
EP-0471236-A1 Imidazopyridine derivatives and their use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-02-19 EP disclosed
US-4341403-A Fluoran compounds, process for preparation thereof, and recording sheets using same FUJI PHOTO FILM CO., LTD. (JP) 1982-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150158901-A1 MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME CCNO, PTGDR, CCNE1 KCNA3 4095/4885PKM 2442/4885MEN1 428/4885
US-20170349621-A1 TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PROKR1, ARG1, ARG2 KCNA3 3973/4885PKM 1963/4885MEN1 1170/4885
US-20250026779-A1 ETHYL MODIFIED RNA CAPS AND METHODS OF USE RNGTT, RNMT, NSUN2 KCNA3 3529/4885PKM 2539/4885MEN1 4439/4885
US-20150250792-A1 ALPHA HYDROXY AMIDES HCAR1, NAA40, HCAR2 KCNA3 3384/4885PKM 4161/4885MEN1 2800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.