SCHEMBL8084660

SCHEMBL8084660

CC(Cl)(Cl)C(Cl)(Cl)CCC(Cl)(Cl)Cl

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2455472 0.73 ALDH1A1 (0.33) TSHR
SCHEMBL6983780 0.72 TSHR (0.36) TSHR
SCHEMBL11049364 0.72 TSHR (0.36) TSHR
SCHEMBL755651 0.67 FDPS (0.38) TSHR
SCHEMBL11027210 0.67 ALDH1A1 (0.67) TSHR
SCHEMBL8204492 0.65 TSHR (0.42) TSHR
SCHEMBL1413945 0.65
SCHEMBL8078563 0.65
SCHEMBL219084 0.62
Trichloroethane SCHEMBL11235795 0.62 TSHR (0.43) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850210-B1 PROCESS FOR THE PREPARATION OF HALOGENATED ALKANES ALLIED SIGNAL INC (US) 2000-09-20 EP disclosed
US-5902914-A Process for the preparation of halogenated alkanes ALLIEDSIGNAL INC. (US) 1999-05-11 US disclosed
CN-1199387-A Process for preparation of halogenated alkanes ALLIED SIGNAL INC (US) 1998-11-18 CN disclosed
EP-0850210-A1 PROCESS FOR THE PREPARATION OF HALOGENATED ALKANES AlliedSignal Inc. (US) 1998-07-01 EP disclosed
WO-1997007083-A1 PROCESS FOR THE PREPARATION OF HALOGENATED ALKANES ALLIEDSIGNAL INC. (US) 1997-02-27 WO disclosed