Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086252 | 0.84 | KMT2A (0.46) | KMT2ALMNATSHRNPC1L3MBTL1 | |
| SCHEMBL14163375 | 0.76 | KMT2A (0.42) | KMT2ALMNATSHRNPC1L3MBTL1 | |
| SCHEMBL763785 | 0.71 | HRH4 (0.37) | KMT2ANPC1MAPTHSP90AB1 | |
| SCHEMBL96485 | 0.68 | — | — | |
| SCHEMBL754084 | 0.67 | KMT2A (0.40) | KMT2ANPC1L3MBTL1MAPTKDM4E | |
| SCHEMBL9155259 | 0.66 | KMT2A (0.33) | KMT2AKDM4EABL1RIN1 | |
| SCHEMBL6360346 | 0.66 | MAPT (0.46) | KMT2ANPC1MAPTKDM4ECYP3A4 | |
| SCHEMBL11769384 | 0.65 | NOS2 (0.40) | — | |
| SCHEMBL13744682 | 0.61 | TSHR (0.59) | KMT2ALMNATSHRNPC1L3MBTL1 | |
| SCHEMBL14020954 | 0.61 | TSHR (0.37) | KMT2ALMNATSHRNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522964-B1 | Compositions to arrest hair loss and to induce and stimulate hair growth based on 2,4-diamino-pyrimidin-3-oxide derivatives | OREAL (FR) | 2000-10-04 | — | — | EP | disclosed |