Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084685 | 0.84 | KMT2A (0.49) | KMT2ATSHRLMNAL3MBTL1NPC1 | |
| SCHEMBL7569936 | 0.76 | KMT2A (0.44) | KMT2ATSHRLMNAL3MBTL1NPC1 | |
| SCHEMBL17400454 | 0.74 | LMNA (0.43) | KMT2ATSHRLMNAL3MBTL1NPC1 | |
| SCHEMBL14163375 | 0.73 | KMT2A (0.42) | KMT2ATSHRLMNAL3MBTL1NPC1 | |
| SCHEMBL6395597 | 0.72 | LMNA (0.39) | KMT2ATSHRLMNAL3MBTL1NPC1 | |
| SCHEMBL763785 | 0.69 | HRH4 (0.37) | KMT2ANPC1MAPTHSP90AB1 | |
| SCHEMBL9159235 | 0.68 | ALDH1A1 (0.35) | KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL1027789 | 0.67 | TKT (0.33) | KMT2ATSHRLMNAL3MBTL1NPC1 | |
| SCHEMBL10872276 | 0.65 | NOS2 (0.38) | CYP2D6CYP2C19 | |
| SCHEMBL23482211 | 0.65 | KDM4E (0.44) | KMT2ATSHRLMNAL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522964-B1 | Compositions to arrest hair loss and to induce and stimulate hair growth based on 2,4-diamino-pyrimidin-3-oxide derivatives | OREAL (FR) | 2000-10-04 | — | — | EP | disclosed |
| EP-0522964-A1 | Compositions to arrest hair loss and to induce and stimulate hair growth based on 2,4-diamino-pyrimidin-3-oxide derivatives | L'OREAL (FR) | 1993-01-13 | — | — | EP | disclosed |