SCHEMBL8084722

SCHEMBL8084722

CCCCC(C)COc1ccc(C=CC(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
ATM Q13315 1/20 0.50
TDP1 Q9NUW8 1/20 0.49
ABCG2 Q9UNQ0 1/20 0.48
KDM4E B2RXH2 4/20 0.47
MAPK1 P28482 1/20 0.47
TAS1R3 Q7RTX0 2/20 0.46
TAS1R1 Q7RTX1 2/20 0.46
POLB P06746 1/20 0.45
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
ALDH1A1 P00352 3/20 0.45
HTT P42858 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
AKR1C3 P42330 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HPGD P15428 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8084721 1.00 THRB (0.50) THRBATMTDP1ABCG2KDM4E
SCHEMBL8081146 0.96 THRB (0.49) THRBATMTDP1ABCG2KDM4E
SCHEMBL8081148 0.96 THRB (0.49) THRBATMTDP1ABCG2KDM4E
SCHEMBL8072163 0.92 THRB (0.53) THRBATMKDM4EMAPK1TAS1R3
SCHEMBL8072161 0.92 THRB (0.53) THRBATMKDM4EMAPK1TAS1R3
SCHEMBL8081593 0.91 THRB (0.51) THRBATMABCG2KDM4EMAPK1
SCHEMBL8081854 0.86 THRB (0.53) THRBATMTDP1ABCG2KDM4E
SCHEMBL8086431 0.86 THRB (0.55) THRBATMKDM4EMAPK1TAS1R3
SCHEMBL8086432 0.86 THRB (0.55) THRBATMKDM4EMAPK1TAS1R3
SCHEMBL2038409 0.86 TDP1 (0.63) THRBATMTDP1ABCG2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed