Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HMGCR | P04035 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39082 | 0.88 | HMGCR (0.57) | GAAMEN1KMT2AHMGCRALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL11660895 | 0.86 | HMGCR (0.55) | GAAMEN1KMT2AHMGCRALDH1A1 | |
| Phenol SCHEMBL20657088 | 0.83 | MEN1 (0.55) | GAAMEN1KMT2AALDH1A1TSHR | |
| Phenol SCHEMBL27499906 | 0.83 | HSPA5 (0.61) | GAAMEN1KMT2AALDH1A1TSHR | |
| Phenol SCHEMBL28093153 | 0.82 | CA12 (0.48) | TSHRLMNACYP2C9BLMNFKB1 | |
| Phenol SCHEMBL28108806 | 0.82 | GABRA1 (0.44) | HMGCRALDH1A1TSHRLMNACYP1A2 | |
| Phenol SCHEMBL3365396 | 0.81 | GAA (0.54) | GAAMEN1KMT2AALDH1A1TSHR | |
| Phenol SCHEMBL28274107 | 0.80 | MEN1 (0.53) | GAAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28049538 | 0.77 | HMGCR (0.38) | GAAHMGCRALDH1A1TSHRLMNA | |
| SCHEMBL8768683 | 0.77 | ESR1 (0.61) | GAAMEN1KMT2AHMGCRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483317-B1 | LOW YELLOWING SCORCH INHIBITOR COMPOSITION | VANDERBILT CO R T (US) | 2011-11-23 | — | — | EP | claimed |