Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.61 |
| ▸ | HMGCR | P04035 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284104 | 0.86 | HMGCR (0.53) | HMGCRALDH1A1TSHRLMNAGAA | |
| SCHEMBL925617 | 0.82 | ESR1 (0.80) | ESR1ESR2ALDH1A1LMNAMEN1 | |
| SCHEMBL14498224 | 0.79 | ESR1 (0.74) | ESR1ESR2TSHRLMNAMAPK1 | |
| SCHEMBL4649854 | 0.78 | ESR1 (0.67) | ESR1ESR2LMNACYP1A2CYP3A4 | |
| Phenol SCHEMBL808474 | 0.77 | GAA (0.50) | HMGCRALDH1A1TSHRLMNAGAA | |
| SCHEMBL39082 | 0.77 | HMGCR (0.57) | HMGCRALDH1A1TSHRLMNAGAA | |
| SCHEMBL21855360 | 0.77 | ESR1 (0.65) | ESR1ESR2LMNACYP1A2CYP3A4 | |
| SCHEMBL1171038 | 0.77 | ESR1 (1.00) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL296781 | 0.77 | ESR1 (1.00) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL547164 | 0.77 | ESR1 (1.00) | ESR1ESR2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621255-B1 | Substituted phenoxy-isobutyric acids and esters | ADIR (FR) | 1997-08-20 | — | — | EP | disclosed |
| EP-0621255-A1 | Substituted phenoxy-isobutyric acids and esters | ADIR ET COMPAGNIE (FR) | 1994-10-26 | — | — | EP | disclosed |