Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MMP9 | P14780 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 9/20 | 0.33 |
| ▸ | CA2 | P00918 | 9/20 | 0.33 |
| ▸ | CA9 | Q16790 | 8/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27788664 | 0.93 | TSHR (0.68) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL8812258 | 0.91 | TSHR (0.65) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL808498 | 0.91 | TSHR (0.65) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL808702 | 0.91 | TSHR (0.65) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL8813122 | 0.91 | TSHR (0.65) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL808789 | 0.91 | TSHR (0.65) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL808518 | 0.91 | TSHR (0.65) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL7663307 | 0.85 | — | — | |
| SCHEMBL29110600 | 0.81 | TSHR (0.64) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL6621065 | 0.79 | ALDH1A1 (0.61) | TSHRUSP2ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678115-B1 | PROCESS FOR PREPARING FUNCTIONAL GROUP-CONTAINING OLEFINIC COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2011-11-16 | — | — | EP | disclosed |
| US-20110264206-A1 | Prosthetic Valve with Sealing Members and Methods of Use Thereof | MEDTRONIC, INC. (US) | 2011-10-27 | — | — | US | disclosed |
| EP-2314559-A2 | Process for preparing functional group-containing olefinic compounds | 3M Innovative Properties Company (US) | 2011-04-27 | — | — | EP | disclosed |
| EP-1678115-A2 | PROCESS FOR PREPARING FUNCTIONAL GROUP-CONTAINING OLEFINIC COMPOUNDS | 3M Innovative Properties Company (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042462-A2 | PROCESS FOR PREPARING FUNCTIONAL GROUP-CONTAINING OLEFINIC COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-05-12 | — | — | WO | disclosed |
| US-6838576-B1 | Process for preparing functional group-containing olefinic compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-01-04 | — | — | US | disclosed |