Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MMP9 | P14780 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 15/20 | 0.33 |
| ▸ | CA2 | P00918 | 15/20 | 0.33 |
| ▸ | CA9 | Q16790 | 14/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA3 | P07451 | 4/20 | 0.32 |
| ▸ | CA4 | P22748 | 4/20 | 0.32 |
| ▸ | CA6 | P23280 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071934 | 0.82 | USP2 (0.58) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL8071936 | 0.82 | USP2 (0.58) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL808479 | 0.81 | TSHR (0.64) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL6621065 | 0.79 | ALDH1A1 (0.61) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL576408 | 0.79 | TSHR (0.88) | TSHRUSP2KDM4EALDH1A1LMNA | |
| Busulfan SCHEMBL4764696 | 0.79 | TSHR (1.00) | TSHRUSP2KDM4EALDH1A1LMNA | |
| Busulfan SCHEMBL4373 | 0.79 | TSHR (1.00) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL4298840 | 0.76 | TSHR (0.94) | TSHRUSP2KDM4EALDH1A1LMNA | |
| Busulfan SCHEMBL7195165 | 0.76 | TSHR (0.94) | TSHRUSP2KDM4EALDH1A1LMNA | |
| SCHEMBL8592211 | 0.76 | TSHR (0.94) | TSHRUSP2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111944012-B | Aromatic amine targeting AR and BET protein degradation chimeric compound and application thereof | 海创药业股份有限公司 | 2023-08-29 | — | — | CN | disclosed |