Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.67 |
| ▸ | APP | P05067 | 5/20 | 0.65 |
| ▸ | ACHE | P22303 | 3/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 4/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MET | P08581 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085011 | 1.00 | FDPS (0.67) | FDPSAPPACHEBCHETTR | |
| SCHEMBL19358969 | 0.94 | APP (0.69) | FDPSAPPACHEBCHETTR | |
| SCHEMBL19358971 | 0.94 | APP (0.69) | FDPSAPPACHEBCHETTR | |
| SCHEMBL2282088 | 0.90 | FDPS (0.67) | FDPSAPPACHEBCHEKDM4E | |
| SCHEMBL6450235 | 0.89 | FDPS (0.66) | FDPSAPPACHEBCHETTR | |
| SCHEMBL6450242 | 0.89 | FDPS (0.66) | FDPSAPPACHEBCHETTR | |
| SCHEMBL28471012 | 0.88 | APP (0.77) | APPTTRMET | |
| SCHEMBL2638677 | 0.87 | FDPS (0.67) | FDPSAPPACHEBCHEKDM4E | |
| SCHEMBL2638679 | 0.87 | FDPS (0.67) | FDPSAPPACHEBCHEKDM4E | |
| SCHEMBL8085985 | 0.87 | KDM4E (0.76) | FDPSACHECNR2CNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887017-A1 | PLANT GROWTH ACCELERATOR | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-12-30 | — | — | EP | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |