SCHEMBL6450235

SCHEMBL6450235

CCCCCOc1ccc(/C=C/C(=O)OCCCCCCOC(=O)CC(=O)OCCCCCCOC(=O)/C=C/c2ccc(OCCCCC)c(OC)c2)cc1OC

nearest known ligand 0.71

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.66
ACHE P22303 6/20 0.63
BCHE P06276 3/20 0.63
APP P05067 4/20 0.60
KDM4E B2RXH2 1/20 0.58
TOP2A P11388 1/20 0.57
TP53 P04637 1/20 0.54
MAPT P10636 1/20 0.54
TTR P02766 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6450242 1.00 FDPS (0.66) FDPSACHEBCHEAPPKDM4E
SCHEMBL2282088 0.90 FDPS (0.67) FDPSACHEBCHEAPPKDM4E
SCHEMBL19358971 0.90 APP (0.69) FDPSACHEBCHEAPPTOP2A
SCHEMBL19358969 0.90 APP (0.69) FDPSACHEBCHEAPPTOP2A
SCHEMBL8085015 0.89 FDPS (0.67) FDPSACHEBCHEAPPKDM4E
SCHEMBL8085011 0.89 FDPS (0.67) FDPSACHEBCHEAPPKDM4E
SCHEMBL2638679 0.88 FDPS (0.67) FDPSACHEBCHEAPPKDM4E
SCHEMBL2638677 0.88 FDPS (0.67) FDPSACHEBCHEAPPKDM4E
SCHEMBL31571350 0.86 FDPS (0.62) FDPSACHEBCHEAPPKDM4E
SCHEMBL2283361 0.86 FDPS (0.62) FDPSACHEBCHEAPPKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1525182-B1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2016-04-06 EP disclosed
EP-1525182-B1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2016-04-06 EP disclosed
US-8436132-B2 Photoactive materials ROLIC AG (CH) 2013-05-07 US disclosed
US-20110236602-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2011-09-29 US disclosed
US-20110236602-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2011-09-29 US disclosed
US-7994273-B2 Photoactive materials ROLIC AG (CH) 2011-08-09 US disclosed
US-7994273-B2 Photoactive materials ROLIC AG (CH) 2011-08-09 US disclosed
US-20100272979-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2010-10-28 US disclosed
US-20100272979-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2010-10-28 US disclosed
US-7750185-B2 Photoactive materials ROLIC AG (CH) 2010-07-06 US disclosed
US-7750185-B2 Photoactive materials ROLIC AG (CH) 2010-07-06 US disclosed
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked ROLIC AG (CH) 2005-12-29 US disclosed
EP-1525182-A1 PHOTOACTIVE MATERIALS Rolic AG (CH) 2005-04-27 EP disclosed
WO-2004013086-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2004-02-12 WO disclosed
EP-1386910-A1 Photoactive materials Rolic AG (CH) 2004-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110236602-A1 PHOTOACTIVE MATERIALS AOC1, CRY1, CCNA1 FDPS 3351/4885ACHE 3662/4885BCHE 4172/4885
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked C9, F12, DAO FDPS 3732/4885ACHE 4613/4885BCHE 4380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.