Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4252190 | 0.91 | ALDH1A1 (0.82) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL4250109 | 0.81 | KDM4E (0.73) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL8085185 | 0.78 | TAAR1 (0.84) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL13701945 | 0.75 | SMN1; SMN2 (0.63) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL10055020 | 0.73 | NPC1 (0.94) | ALDH1A1KMT2ARAB9AHTTRXFP1 | |
| SCHEMBL3638734 | 0.72 | TAAR1 (0.82) | ALDH1A1MAPTLMNAKDM4EHPGD | |
| SCHEMBL3647714 | 0.72 | TAAR1 (0.82) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL8703351 | 0.72 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL4251968 | 0.72 | RXFP1 (0.94) | ALDH1A1KMT2AMEN1KDM4ERAB9A | |
| SCHEMBL30862297 | 0.72 | RXFP1 (0.94) | ALDH1A1KMT2AMEN1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |