Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.84 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3645707 | 0.91 | TAAR1 (1.00) | TAAR1MAPTALDH1A1SMN1; SMN2SLC2A1 | |
| SCHEMBL3641066 | 0.83 | TAAR1 (0.70) | TAAR1MAPTSMN1; SMN2TP53 | |
| SCHEMBL3647714 | 0.81 | TAAR1 (0.82) | TAAR1MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL3638734 | 0.81 | TAAR1 (0.82) | TAAR1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4257413 | 0.80 | TAAR1 (0.81) | TAAR1MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4254513 | 0.80 | TAAR1 (0.79) | TAAR1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4248051 | 0.79 | TAAR1 (0.78) | TAAR1MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8085243 | 0.78 | ALDH1A1 (0.68) | TAAR1MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL3645068 | 0.76 | TAAR1 (0.65) | TAAR1MAPTSMN1; SMN2TP53 | |
| SCHEMBL3679927 | 0.76 | TAAR1 (0.72) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |