SCHEMBL808526

SCHEMBL808526

O=C(O)COc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.71
ALDH1A1 P00352 2/20 0.66
MAPK1 P28482 2/20 0.66
LMNA P02545 2/20 0.66
CYP1A2 P05177 2/20 0.66
PGR P06401 2/20 0.66
SLC6A2 P23975 2/20 0.66
CYP2C19 P33261 2/20 0.66
CYP2D6 P10635 1/20 0.66
PDE4A P27815 1/20 0.66
HRH1 P35367 1/20 0.66
HTT P42858 1/20 0.66
SLC6A3 Q01959 1/20 0.66
PDE4D Q08499 1/20 0.66
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
USP2 O75604 1/20 0.61
GAA P10253 1/20 0.61
KEAP1 Q14145 1/20 0.61
NFE2L2 Q16236 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30538666 1.00 HPGD (0.71) HPGDALDH1A1MAPK1LMNACYP1A2
SCHEMBL15721416 0.89 PPARD (0.66) HPGDALDH1A1MAPK1LMNACYP1A2
SCHEMBL9061560 0.88 HPGD (0.68) HPGDALDH1A1MAPK1LMNACYP1A2
SCHEMBL12415232 0.88 HPGD (0.69) HPGDALDH1A1MAPK1LMNACYP1A2
SCHEMBL12743862 0.88 LMNA (0.69) HPGDALDH1A1MAPK1LMNACYP1A2
SCHEMBL16092725 0.86 MEN1 (0.61) HPGDALDH1A1MAPK1LMNACYP1A2
SCHEMBL10557539 0.86 HPGD (0.68) HPGDALDH1A1MAPK1LMNACYP1A2
SCHEMBL545524 0.86 HPGD (0.68) HPGDALDH1A1MAPK1LMNACYP1A2
SCHEMBL23102027 0.86 HPGD (0.65) HPGDALDH1A1MAPK1LMNACYP1A2
SCHEMBL320631 0.86 HPGD (0.69) HPGDALDH1A1MAPK1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11229590-B2 Sunscreen formulation SUN YIMIN (CN) 2022-01-25 US claimed
US-20210361548-A1 A SUNSCREEN FORMULATION SUN YIMIN (CN) 2021-11-25 US claimed
CN-111542297-A Sunscreen formulations 孙益民 2020-08-14 CN claimed
JP-1070453-A None JP disclosed
US-20230285258-A1 A SUNSCREEN FORMULATION SUN YIMIN (CN) 2023-09-14 US disclosed
US-20230285258-A1 A SUNSCREEN FORMULATION SUN YIMIN (CN) 2023-09-14 US disclosed
CN-112789026-B Sun protection preparation 孙益民 2023-09-05 CN disclosed
US-11229590-B2 Sunscreen formulation SUN YIMIN (CN) 2022-01-25 US disclosed
US-11229590-B2 Sunscreen formulation SUN YIMIN (CN) 2022-01-25 US disclosed
US-20210361548-A1 A SUNSCREEN FORMULATION SUN YIMIN (CN) 2021-11-25 US disclosed
US-20210361548-A1 A SUNSCREEN FORMULATION SUN YIMIN (CN) 2021-11-25 US disclosed
EP-0742259-A1 Latent mercaptans as multi-functional additives for halogen-containing polymer compositions MORTON INTERNATIONAL, INC. (US) 1996-11-13 EP disclosed
EP-0675108-A1 Thioether substituted hydroxybenzophenones and stabilized compositions CIBA-GEIGY AG (CH) 1995-10-04 EP disclosed
EP-0303283-B1 2-HYDROXYBENZOPHENONE HYDRAZIDES AND DERIVATIVES THEREOF ATOCHEM NORTH AMERICA, INC. (US) 1993-02-03 EP disclosed
EP-0303283-A2 2-Hydroxybenzophenone hydrazides and derivatives thereof ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed
US-4342875-A STABILIZERS FOR OLEFIN POLYMERS CINCINNATI-MILACRON, INC. (US) 1982-08-03 US disclosed
US-RE29523-E Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds BORG-WARNER CORPORATION (US) 1978-01-24 US disclosed
US-4064100-A HEAT AND LIGHT STABILIZERS FOR POLYMERS, CONTAINERS FOR FOOD WESTON CHEMICAL CO., INC. (US) 1977-12-20 US disclosed
US-4012399-A ULTRAVIOLET LIGHT ABSORBERS AND STABILIZERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1977-03-15 US disclosed
US-4000101-A POLYPROPYLENE WESTON CHEMICAL CORPORATION (US) 1976-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210361548-A1 A SUNSCREEN FORMULATION CUTA, BCAS2, SUN2 HPGD 124/4885ALDH1A1 598/4885MAPK1 3991/4885
US-11229590-B2 Sunscreen formulation BCAS2, CUTA, SUN2 HPGD 123/4885ALDH1A1 685/4885MAPK1 3843/4885
US-20230285258-A1 A SUNSCREEN FORMULATION CUTA, NISCH, SUN2 HPGD 546/4885ALDH1A1 1380/4885MAPK1 4137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.