Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085341 | 0.87 | ABCC9 (0.43) | ABCC9KDM4EABCB1 | |
| SCHEMBL7323133 | 0.87 | ABCC9 (0.39) | ABCC9KDM4EABCB1KCNE1KCNQ1 | |
| SCHEMBL8076948 | 0.82 | ABCC9 (0.43) | ABCC9KDM4EABCB1 | |
| SCHEMBL7325892 | 0.80 | KDM4E (0.38) | ABCC9KDM4EABCB1KCNE1KCNQ1 | |
| SCHEMBL7325363 | 0.80 | KDM4E (0.38) | ABCC9KDM4EABCB1KCNE1KCNQ1 | |
| SCHEMBL8088687 | 0.79 | ABCC9 (0.57) | ABCC9KDM4EABCB1KCNE1KCNQ1 | |
| SCHEMBL7326400 | 0.78 | ABCC9 (0.43) | ABCC9KDM4EABCB1 | |
| SCHEMBL7324552 | 0.73 | ABCC9 (0.40) | ABCC9KDM4EABCB1 | |
| SCHEMBL9144225 | 0.73 | ABCC9 (0.46) | ABCC9KDM4EABCB1CYP1A2CYP2D6 | |
| SCHEMBL10519818 | 0.72 | ABCC9 (0.44) | ABCC9KDM4EABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5425938-A | Coametics | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1995-06-20 | — | — | US | disclosed |
| US-5387587-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |