Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20548111 | 0.86 | PDE10A (0.54) | PDE10ATRPV3 | |
| SCHEMBL29228864 | 0.84 | PDE10A (0.55) | PDE10ATRPV3 | |
| SCHEMBL16516277 | 0.83 | PDE10A (0.58) | PDE10ATRPV3 | |
| SCHEMBL23207442 | 0.79 | PDE10A (0.54) | PDE10ATRPV3 | |
| SCHEMBL15537495 | 0.79 | TRPV3 (0.58) | PDE10ATRPV3 | |
| SCHEMBL10233469 | 0.79 | PDE10A (0.57) | PDE10ATRPV3 | |
| Hydrochloric Acid SCHEMBL30152537 | 0.78 | PDE10A (0.52) | PDE10ATRPV3 | |
| Hydrochloric Acid SCHEMBL23167793 | 0.78 | PDE10A (0.52) | PDE10ATRPV3 | |
| SCHEMBL6242988 | 0.78 | HSD11B1 (0.50) | PDE10ATRPV3 | |
| SCHEMBL6838679 | 0.78 | HSD11B1 (0.50) | PDE10ATRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6133270-A | Isothiazolones and pharmaceutical formulations | WARNER-LAMBERT COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| US-6001863-A | USEFUL AS ANTIVIRAL, ANTIINFLAMMATORY AND ANTIATHEROSCLEROSIS AGENT; ADMINISTERING TO THE PATIENT IN NEED OF ZINC EJECTION FROM NUCLEOCAPSID PROTEIN | WARNER-LAMBERT COMPANY (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0828488-A1 | ISOTHIAZOLONES | WARNER-LAMBERT COMPANY (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038144-A1 | ISOTHIAZOLONES | WARNER-LAMBERT COMPANY (US) | 1996-12-05 | — | — | WO | disclosed |