Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 4/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085842 | 0.83 | ALDH1A1 (0.42) | MAPTTDP1PKMKMT2AALDH1A1 | |
| SCHEMBL8090408 | 0.74 | KMT2A (0.41) | MAPTPKMKMT2AALDH1A1 | |
| SCHEMBL4063606 | 0.74 | MEN1 (0.44) | KMT2AALDH1A1 | |
| SCHEMBL5973317 | 0.69 | NQO2 (0.40) | MAPTTDP1KMT2ATYMSALDH1A1 | |
| SCHEMBL8078887 | 0.69 | POLB (0.41) | MAPTTDP1PKMKMT2ATYMS | |
| SCHEMBL8086966 | 0.68 | ALDH1A1 (0.39) | MAPTKMT2AALDH1A1 | |
| SCHEMBL8085722 | 0.68 | ALDH1A1 (0.42) | MAPTKMT2AALDH1A1 | |
| SCHEMBL8078916 | 0.68 | TRPV1 (0.48) | MAPTKMT2AALDH1A1 | |
| SCHEMBL8078889 | 0.68 | HTT (0.39) | MAPTPKMKMT2ATYMSALDH1A1 | |
| SCHEMBL27462958 | 0.68 | GRK6 (0.37) | MAPTTDP1PKMKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080743-A | AS CHEMICAL INTERMEIDATES FOR PREPARING DRUGS | NOVARTIS AG (CH) | 2000-06-27 | — | — | US | disclosed |
| EP-0853617-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | Novartis AG (CH) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997008155-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |