Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086955 | 0.91 | TRPV1 (0.37) | ALDH1A1MAPTRXFP1SMN1; SMN2TRPV1 | |
| SCHEMBL8078916 | 0.88 | TRPV1 (0.48) | ALDH1A1MAPTTRPV1MEN1KMT2A | |
| SCHEMBL8085722 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTRXFP1SMN1; SMN2TRPV1 | |
| SCHEMBL8090408 | 0.85 | KMT2A (0.41) | ALDH1A1MAPTRXFP1SMN1; SMN2GLA | |
| SCHEMBL8183409 | 0.84 | TRPV1 (0.39) | ALDH1A1MAPTRXFP1SMN1; SMN2TRPV1 | |
| SCHEMBL27462958 | 0.78 | GRK6 (0.37) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL8078887 | 0.78 | POLB (0.41) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8091960 | 0.78 | ALOX5 (0.51) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8086968 | 0.77 | CTSB (0.43) | ALDH1A1MAPTKMT2A | |
| SCHEMBL8078889 | 0.76 | HTT (0.39) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080743-A | AS CHEMICAL INTERMEIDATES FOR PREPARING DRUGS | NOVARTIS AG (CH) | 2000-06-27 | — | — | US | disclosed |