Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27643987 | 0.87 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1HPGDHTTGAA | |
| SCHEMBL10584504 | 0.81 | POLB (0.57) | POLBL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL11380018 | 0.80 | POLB (0.67) | POLBALDH1A1HTTKDM4E | |
| SCHEMBL7569415 | 0.80 | KDM4E (0.60) | POLBL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL3559044 | 0.79 | POLB (0.62) | POLBL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL10978862 | 0.78 | HDAC3 (0.55) | POLBL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL10978779 | 0.78 | HDAC3 (0.55) | POLBL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL10990471 | 0.78 | HDAC3 (0.55) | POLBL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL10978062 | 0.78 | HDAC3 (0.55) | POLBL3MBTL1ALDH1A1HPGDHTT | |
| SCHEMBL10988684 | 0.78 | HDAC3 (0.55) | POLBL3MBTL1ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |