Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | THRB | P10828 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | GFER | P55789 | 2/20 | 0.60 |
| ▸ | PLEC | Q15149 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10584504 | 0.84 | POLB (0.57) | KDM4EALDH1A1MAPTTHRBHPGD | |
| SCHEMBL7568209 | 0.84 | HDAC3 (0.50) | KDM4EALDH1A1GAAMAPTTHRB | |
| SCHEMBL8396604 | 0.82 | GAA (0.56) | KDM4EALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL27757715 | 0.81 | HDAC1 (0.62) | POLBHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7569087 | 0.81 | SELL (0.62) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL11380018 | 0.80 | POLB (0.67) | KDM4EALDH1A1HTTPOLB | |
| SCHEMBL8085964 | 0.80 | POLB (0.52) | KDM4EALDH1A1GAAHPGDHTT | |
| SCHEMBL9525197 | 0.79 | KDM4E (0.72) | KDM4EALDH1A1GAAMAPTTHRB | |
| SCHEMBL10978862 | 0.79 | HDAC3 (0.55) | KDM4EALDH1A1GAAMAPTTHRB | |
| SCHEMBL10978779 | 0.79 | HDAC3 (0.55) | KDM4EALDH1A1GAAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685470-B1 | Benzene derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0685470-A2 | Benzene derivatives and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1995-12-06 | — | — | EP | disclosed |